![]() ![]() selenium-75 for industrial radiography.fermium-257 for heavy element chemistry research.berkelium-249, americium-243, plutonium-242, californium-251, einsteinium-255, and curium-248 for use as targets for discovery of new super heavy elements.cadmium-109 for X-ray fluorescence imaging and environmental research.bismuth-213, lead-212, astatine-211, copper-67, thorium-227, and radium-223 for cancer and infectious disease therapy and research.americium-241 and californium-252 for oil/gas exploration and production well logging.actinium-225, actinium-227, tungsten-188, lutetium-177, strontium-89, strontium-90, and cobalt-60 for cancer therapy.The National Isotope Development Center (NIDC) is located at Oak Ridge National Laboratory (ORNL) and is responsible for the day-to-day business operations of the Program, including sales, contract negotiation, marketing assessment, public outreach, quality control, and packaging and transportation. The DOE IP also considers DOE-owned legacy waste or inventories and extracts isotopes of interest to re-purpose unwanted or excess materials. The DOE IP has developed and implemented modern stable isotope enrichment capabilities to replenish supplies housed in the National Stable Isotope Repository and promote U.S. to be dependent on foreign sources for certain stable isotopes. inventory of stable isotopes is limited or has even been depleted in some cases, causing the U.S. ![]() The latter consists of enriched stable isotopes created by calutrons (electromagnetic ion separation) that were developed as part of the Manhattan Project, the calutrons ceased operations in 1998. The DOE IP manages federal inventories of key isotopes, such as helium-3 for cryogenics and other applications, and the National Stable Isotope Repository. These disciplines are foundational, not only to isotope production and processing, but underpin many critical aspects of basic and applied nuclear and radiochemical science. The R&D activities provide collateral benefits for training, workforce development, and promotion of a future U.S.-based expertise relevant to nuclear energy, accelerator science, nuclear engineering, nuclear physics, isotope enrichment, and nuclear chemistry and radiochemistry. The DOE IP supports world-leading research and development (R&D) associated with creating novel and more efficient isotope production and processing techniques. industry to ensure availability of adequate, high quality isotope supply for continued stability and planned growth and facilitates commercialization of isotope production to the domestic private sector. The DOE IP utilizes particle accelerators, nuclear reactors, enrichment technologies, and radiochemical processing capabilities throughout the national laboratory complex and at universities that it stewards, or leverages capabilities stewarded by other federal programs or academic institutions to most cost effectively utilize national capabilities to meet the requirements of the nation in isotope demand. Isotopes can directly enable emerging technology, and contribute to the economic, technical and scientific strength of the United States. Isotopes are high-priority commodities of strategic importance for the nation and are essential in medical diagnosis and treatment, discovery science, national security, industrial processes and manufacturing, space exploration and communications, biology, archeology, quantum science and other fields. The Program is typically the only, or one of few, global producers for these novel isotopes. ![]() The DOE IP produces critical radioactive and stable isotopes in short supply for the nation or that no domestic entity has the infrastructure or core competency to produce. The Program supplies isotopes and related services to the Nation under the Atomic Energy Act of 1954 and has the sole authority within DOE to produce isotopes for sale and distribution. The DOE Isotope Program (DOE IP), and its predecessor organizations, has been at the forefront of the development and production of radioactive and stable isotopes that are used worldwide. ![]()
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